Treatment of Cutaneous Atrophy After Corticosteroid Injection, With Heterologous Type I Collagen

Steroid-induced atrophy is a well-documented complication of intralesional steroid use with an estimated incidence varying from 1.5% to 40%. Cutaneous atrophy usually begins within 2 to 3 months of injection and regresses within 1 to 2 years. However, it has also  been reported to persist beyond 5 years.1 Treatment modalities that have been used to restore cutaneous atrophy include autologous fat injection, fat grafting, hyaluronic acid filler, pulsed dye laser, and intralesional bacteriostatic saline. We present 2 cases of steroid injection-induced atrophy treated with heterologous type I collagen (HTIC) (Linerase Collagen, Typeone Biomaterials Srl, Lecce, Italy).

 

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